Applied biopharmaceutics & pharmacokinetics / Leon Shargel, Andrew B.C. Yu, Susanna Wu-Pong.
By: Shargel, Leon.
Contributor(s): Yu, Andrew B. C | Wu-Pong, Susanna.
Material type:
BookPublisher: New York : McGraw-Hill, 2013Edition: 6th ed. International Edition.Description: xviii, 811 p. ; 23 cm. illustrations.ISBN: 9781259071409.Other title: Applied biopharmaceutics and pharmacokinetics.Subject(s): Biopharmaceutics | Pharmacokinetics | Biopharmaceutics | Models, Chemical | Pharmacokinetics| Current location | Call number | Copy number | Status | Date due | Item holds |
|---|---|---|---|---|---|
| University of Santo Tomas-Legazpi Main Library | Circ. RM301.4 .Sh531 (Browse shelf) | 1 | Available |
Includes bibliographical references and index.
Introduction to biopharmaceutics and pharmacokinetics -- Mathematic fundamentals in pharmacokinetics -- One-compartment open model: intravenous bolus administration -- Multicompartmental models : intravenous bolus administration -- Intravenous infusion -- Drug elimination and clearance -- Pharmacokinetics of oral absorption -- Multiple-dosage regimens -- Nonlinear pharmacokinetics -- Physiologic drug distribution and protein binding -- Drug elimination and hepatic clearance -- Pharmacogenetics -- Physiologic factors related to drug absorption -- Biopharmaceutic considerations in drug product design and in vitro drug product performance -- Drug product performance, in vivo : bioavailability and bioequivalence -- Impact of drug product quality and biopharmaceutics on clinical efficacy -- Modified-release drug products -- Targeted drug delivery systems and biotechnology products -- Relationship between pharmacokinetics and pharmacodynamics -- Application of pharmacokinetics to clinical situations -- Dosage adjustment in renal and hepatic disease.
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